The plot of the third season of the cult Series "Gangster Petersburg" brings together the main adversaries of the city’s “godfather,” Viktor Pavlovich Govorov, nicknamed Antibiotic, who have decided to put an end to the crime boss once and for all. Major Nikita Kudasov of the Ministry of Internal Affairs agrees to work alongside journalist Andrei Obnorsky, who dreams of taking revenge on Antibiotic for the deaths of several friends and family members. Govorov himself intends to pressure Kudasov into releasing his henchmen from prison. Meanwhile, a certain Rachel Dallet declares a hunt for Antibiotic, hiring the old man Korablyov as a hitman, whose past is very, very murky. Obnorsky, meanwhile, hopes to bring down Antibiotic using the compromising material he has collected, which was shared with him by Sergei Chelishchev, the main character of the previous season. After meeting a mysterious woman at a fitness club who keeps photographs of Chelishchev and Oleg Zvantsov in a pendant, Andrei decides to find out who she is and what she wants. At the same time, retired Chekists embark on a profitable operation involving Finnish vodka.